PSI TBI-0310 CCI Instrument

TBI-0310 CCI Instrument

PSI engineers have developed a computer controlled cortical contusion device (CCI) designed specifically for medical research using transgenic mice. This system provides researchers specializing in head trauma injury with a unique tool to evaluate the cause and extent of traumatic brain injuries that removes the guess work.

SKU: TBI0310 Category:

Description

A brain contusion device designed for research using rats and mice

This system provides researchers specializing in traumatic brain injury a unique instrument to evaluate the mechanisms underlying brain trauma. The instrument enables the application of  standard contusion injuries to the brains of small rodents. The amount of cortical depression is user-selectable between 0 and 3.5 mm (0.01 mm increments). The target velocity of the impacting tip is electronically monitored and is user-selectable between 1.5 and 6.0 m/sec (0.1m/s increments). Dwell time, defined as the amount of time the cortical tissue remains depressed at the preset depression level, is user-selectable between 50 milliseconds and 5 seconds (in 1 millisecond increments). The system is ready to use out of the box when combined with a user-supplied stereotaxic frame1. All necessary electrical components are contained within a control box. No additional computer interface is required. The control unit touch-screen display guides the investigator through the injury sequence for maximum reproducibility and ease of operation. The output display shows the measured final impact velocity, dwell time, and cortical displacement achieved during the injury sequence.

The TBI-0310 system utilizes a unique contact sensor mechanism that ensures accurate, reliable, and repeatable detection of the cortical surface prior to initiating the injury sequence.  This unique feature distinguishes it from competing devices by removing any subjective experimental setup that may vary between operators and/or animals.

The TBI-0310 yields the ultimate in accuracy and reproducibility in brain injury modeling. 

Specifications

Impactor:

  • Maximum height — 29″ (736 mm)
  • Desk top foot print X and Y — 18″ (457mm) by 18″ (457mm)
  • Weight — 49 lbs (22 kg)
  • Cylinder — Pneumatic (compressed air)
  • Everything is included but stereotaxic frame (the Power train, contact sensor, and control unit included)
  • 2-axis manual stereotaxic frame position controller, Range 3″ x 8″ (276 x 203 mm)
  • Motor driven Z axis, Range — 4″ (102mm)
  • Removable plate for stereotaxic frame, 15″ x 8″ (381 x 203 mm)
  • Standpost for stereotaxic frame customized to users specification and compatible with all major brands of stereotaxic frames

Control Unit:

  • Cabinet — 14.4″ (36.6cm) x 11.5″ (29.2cm) 7.2″ (18.3cm)
  • Weight — 14 lbs (6.4 kg)
  • Display — Color Touch Screen 4.5″ x 3.5″ (11.5mm x 9mm)
  • Programmable impact depth level 0-3.5 millimeters
    • Increments of 0.01 millimeters
  • Programmable impact velocity — 1.5-6.0 meters/sec
    • Increments of 0.1 meters/sec
  • Programmable impact dwell time — 50 milliseconds – 5.0 seconds
    • Default = 500 milliseconds
    • Increments of 1.0 milliseconds
  • Power options2
    • 120 or 240VAC
    • 50 or 60 HZ
    • 1 amp

Air Compressor:

  • Jun-Air Model 3-4
  • Compressor foot print X and Y — 15″ (381mm) x 12″ (305mm)
  • Near silent noise level — 35dB(A)/1m
  • Maximum system pressure — 120 psi
  • Weight — 40 lbs (18kg)
  • Power options2
    • 120 or 240VAC
    • 50 or 60 HZ
    • 5 amps

Removable impact tips

  • Standard mouse tip size — 3mm
  • Standard rat tip size — 5mm
  • Custom tip sizes and shapes can be made to order

1Please contact PSI for recommendations and details on the user supplied stereotaxic frame..
2Please Specify power requirement with order.

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